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Calcium Regulation & Bone Metabolism V9 Basic & Clinical Aspects (Developments in Psychiatry) by David Ed Cohn

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Published by Excerpta Medica .
Written in English


Book details:

Edition Notes

ContributionsDavid V. Cohn (Other Contributor)
The Physical Object
Number of Pages991
ID Numbers
Open LibraryOL7531893M
ISBN 100444808833
ISBN 109780444808837

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The maintenance of a constant calcium ion concentration in extracellular fluid plays a central role in the control of bone metabolism. Bone is also important in the regulation of magnesium, phosphate, sodium, and hydrogen ions, and under certain circumstances, the control systems depends on these ions and on calcium as tomsseweranddrainserviceoh.com by: May 29,  · 1. Introduction. Defects in calcium (Ca 2+) homeostasis and bone mineral metabolism are major causes of morbidity and mortality in elderly chronic kidney disease (CKD) patients, a steadily growing population worldwide [].In this paper, the role of Ca 2+ and its dysregulation in elderly CKD is given special consideration, incorporating the most recent advances in tomsseweranddrainserviceoh.com by: A SYMBOLIC MODEL FOR THE REGULATION BY BONE METABOLISM OF THE BLOOD CALCIUM LEVEL IN RATS JEAN-PAUL AUBERT and FELIXBRONNER From the Laboratoire des Isotopes, Institut Pasteur, Paris, and the Department of Physiology and Biophysics, University of Louisville School of Medicine, Louisville, Kentucky ABSTRACT The control by bone metabolism of the blood calcium Cited by: Calcium metabolism or calcium homeostasis is the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcemia or hypocalcemia, both of which can have important consequences for health. Although calcium flow to and from the bone is neutral, about five mmol is turned over a day.

Bone Metabolism • Bone acts as a reservoir for calcium and phosphate • Bone remodeling allows for release and uptake of calcium – thus one control of bone remodeling is calcium level • Bone remodeling is a constant, not random process – always going on but rate determined at multiple levels – Hormone – PTH, Vitamin D. The regulation of bone and bone mineral metabolism results from the interactions of four hormones – parathyroid hormone (PTH), calcitonin (CT), fibroblast growth factor 23 (FGF23) and vitamin D (VD) – at three target organs – bone, kidneys, and GI tract – to regulate three bone minerals – calcium, magnesium, and tomsseweranddrainserviceoh.com by: 7. Calcium as a nutrient is most commonly associated with the formation and metabolism of bone. Over 99 percent of total body calcium is found as calcium hydroxyapatite (Ca10[PO4]6[OH]2) in bones and teeth, where it provides hard tissue with its strength. Calcium in the circulatory system, extracellular fluid, muscle, and other tissues is critical for mediating vascular contraction and Cited by: 2. Nov 28,  · Regulation by parathyroid hormone (PTH) • Parathyroid hormone (PTH) is secreted by two pairs of parathyroid glands • Parathyroid hormone (mol. wt. Mechanism of action of PTH • Action on the bone: • PTH causes decalcification or demineralization of bone, a process carried out by .

The transient loss of bone mass during lactation can compromise skeletal strength and lead to fragility fractures in some women. But the vast majority of women can be assured that the changes in calcium and bone metabolism during pregnancy and lactation are normal, healthy, and without adverse consequences in the tomsseweranddrainserviceoh.com by: 6. Oct 18,  · Calcium is only available to the body through dietary intake. In the elderly there is inadequate intestinal absorption of calcium combined with an age-related hormonal decline, which results in adverse effects on bone health. 2,3 1,Dihydroxyvitamin D 3 [1,25 (OH) 2 D 3 ], the hormonally active form of vitamin D, Cited by: Although the calcium circulating in your blood comprises less than 1 percent of your total body calcium, maintaining appropriate levels is vital for bone health and normal muscle and nerve function. Three principal hormones regulate blood calcium levels: parathyroid hormone, vitamin D and calcitonin. Calcium metabolism is the movement and regulation of calcium ions in and out of the body, and between body compartments: the blood plasma, the extracellular and intracellular fluids, and bone. Bone acts as a calcium storage center for deposits and withdrawals as needed by the blood via continual bone remodeling.– An important aspect of calcium metabolism is plasma calcium homeostasis, the regulation of calcium ions in the blood .